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| eISSN: | 2583-1194 |
ORIGINAL RESEARCH PAPER
GCMS, Antimicrobial and Antiadherence Analysis of Rosa damascena extract on Dental Pathogens: An In Vitro Study
1
College of Dentistry, Department of Restorative Dental Science, Jazan University, Saudi Arabia
2
Department of Clinical Practice, College of Pharmacy, Jazan university, Saudi Arabia
3
Department of Microbiology, Sadakathullah Appa College, India
Submission date: 2025-10-02
Final revision date: 2025-10-13
Acceptance date: 2026-01-25
Online publication date: 2026-03-26
Corresponding author
Syed Nahid Basheer
College of Dentistry, Department of Restorative Dental Science, Jazan University, Saudi Arabia
College of Dentistry, Department of Restorative Dental Science, Jazan University, Saudi Arabia
KEYWORDS
TOPICS
ABSTRACT
Formulations of Rosa damascena extracts were prepared, thereafter subjected to GC-MS analysis, and evaluated for antibacterial, antifungal, and antiadherence characteristics against two particular microorganisms implicated in dental disease. The aim was to determine whether the extracts would inhibit the growth of microorganisms. Studies on minimum inhibitory concentrations indicated that the turbid growth seen in broth tubes was inhibited by 400 μg/ml of methanol extract. The standard agar diffusion method was used to assess the antibacterial properties of Rosa damascena ethanol and methanol extracts. Methanol extracts exhibited the strongest effectiveness against both dental pathogens. The inhibitory zones of methanol extracts (300 μg/ml and 400 μg/ml)against Streptococcus mutans were 12.6 ± 0.75 mm and 15.9 ± 0.57 mm, while the inhibitory zones against Candida albicans were approximately 12.9 ± 0.57 mm and 15.6 ±0.75 mm. When tested for anti-adherence, Rosa damascena extracts significantly reduced the number of organisms attached to glass specimens. According to the results, extracts from Rosa damascena may be used as an ingredient in formulations for natural remedies. However, more research is needed.
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