Effect of Nanopraticles of Achillea Millefolium Oil against Pathogenic Bacteria and Antioxidant Activity

Abstract

The potential of yarrow (Achillea millefolium) as a drug in folk medicine is of interest because of its medicinal applications. The antibacterial, and antioxidant activities and the chemical characteristics of the essential oil nanoparticles were investigated in this study. The silver nanoparticles were studied using the UV-vis spectroscopy, FTIR, GC-MS, and atomic force microscopy. The antibacterial efficacy of the nanoparticles was assessed against different bacteria, such as Escherichia coli, Staphylococcus aureus, Streptococcus pyogenes, and Klebsiella pneumoniae, employing the well diffusion method. It was employed for its  DPPH radical scavenging activity and its antioxidant effects. The production of NPs was established by the color change and the spectral shift observed at 219 nm using UV-vis spectroscopy, which indicated that there was a surface plasmon resonance peak at λ = 219 nm. The resulting AgNPs exhibited a spherical morphology with an average diameter of approximately 57.80 nm. The analysis of  the FTIR spectra of the  A. millefolium oil nanoparticles revealed functional groups. Certain chemicals in these nanoparticles were identified through GC-MS studies. The antibacterial and antioxidant efficacy of A. millefolium essential oil nanoparticles was significant. It was concluded that AgNPs  of A. millefolium have antibacterial and antioxidant activities.