Lived Experiences of Patients after Peripheral Blood Allogeneic Hematopoietic Stem Cell Transplantation: A mixed-method study

Abstract

Background: Recovery after allogeneic peripheral blood stem cell transplantation (PBSCT) is often evaluated through clinical endpoints, yet survivors also manage persistent bodily, emotional, family, and financial challenges after discharge. This study explored the lived experiences and supportive care needs of adult PBSCT survivors in Egypt. Methods: A qualitative-dominant exploratory mixed-method design was used in hematology and bone marrow transplantation outpatient clinics. Sixty adult survivors completed a demographic and clinical data sheet to contextualize the sample. A purposively selected subsample of 20 survivors completed three qualitative contacts: one in-person interview and two follow-up telephone calls. Interviews were audio-recorded, transcribed verbatim in Arabic, translated for reporting, thematically analyzed, and interpreted alongside descriptive findings. Results: Participants were 19-55 years old (mean 38.6 +/- 9.2); 56.7% were male, 66.7% were married, 63.3% reported inadequate income, and 45.0% reported post-transplant complications. Six themes were identified: living in a fragile body; uncertainty as a daily companion; rebuilding life and roles; coping through meaning and discipline; support gaps and financial strain; and the healthcare relationship. Conclusion: Post-PBSCT survivorship was clinically and socially complex. Follow-up care should extend beyond complication surveillance to include fatigue assessment, symptom guidance, family-inclusive support, financial awareness, culturally meaningful coping, and clear communication pathways.